Monoallelic loss of PTEN and ARID1A is identified in normal colonic epithelium. The resulting haploinsufficient phenotypes ...

Jan. 30, 2025 — A new study has highlighted the potential of resveratrol, a natural compound found in grapes, blueberries, and raspberries, to enhance female fertility. The systematic review ...

Jan. 31, 2025 — Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders -- T cells -- lose their ability to ...

Thymus seeding progenitors (TSPs) are a heterogeneous group of multipotent progenitors that migrate to the thymus via CCR7 and CCR9 receptors. While NOTCH guides thymus progenitors toward T cell fate, ...

January 2025 If you haven’t looked at what your cell phone bill might be under a new plan or on a new service, you should check now. In recent years prices have come down and data allocations ...

Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells do not express ...

The identified signatures were then associated with longitudinal clinical variables after treatment. Differential gene expression and cellular convolution were used to define key regulated genes and ...

Bone-marrow-derived multipotent progenitor stromal cells — or mesenchymal stem cells (MSCs) — are the common predecessors of cells of the mesenchymal lineage, such as bone, cartilage and fat ...

2 Ipatimup – Institute of Molecular Pathology and Immunology of the University of Porto, Porto, Portugal 3 Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto, Porto, Portugal ...

Li Dak Sum & Yip Yio Chin Center for Stem Cells and Regenerative Medicine, and Department of Orthopedic Surgery of ... and investigated the stage-specific and location-specific pathology of cartilage ...

Angina may result from systemic disorders, such as hypertension, or myocardial pathology such as hypertrophic cardiomyopathy, which involves remodelling of intramural coronary arterioles, vascular ...

To date, several tissue-, cell-, molecular-, and imaging-based biological ageing markers have been developed, such as DNA-methylation status, brain age and three-dimensional (3D) facial age.5–8 ...