In a collaborative effort, researchers at the University of Amsterdam and the HFML-FELIX institute in Nijmegen have been able ...

This transformation relies on radical mechanisms based on hydrogen ... a radical cation that initiates the intramolecular C(sp3)–N bond forming reaction. “HFIP is a fascinating yet intriguing ...

The Friedel-Crafts acylation of an aromatic compound introduces an acyl group into the aromatic ring to form a new carbon-carbon bond [1] [2] [3]. The acylarenes produced by this reaction are ...

Key Laboratory of Mesoscopic Chemistry of Ministry of Education, School of Chemistry and Chemical Engineering, Institute of Theoretical and Computational Chemistry, Nanjing University, Nanjing, China ...

1 Arrhenius Laboratory, Department of Organic Chemistry, Stockholm University, Stockholm, Sweden 2 Department of Chemistry and Chemical Biology, Indiana University-Purdue University Indianapolis, ...

However, the RC reactions involving allenoate substrates are very rare, and in particular, asymmetric intramolecular RC reaction of allenoates is yet to be discovered. Here, we show that the ...

To address the reaction mechanisms that could plausibly explain ... In short, the dehydrogenation of the β-ethyl groups followed by the intramolecular electrocyclization of the resulting ethenyl ...

Unexpected reaction mechanisms and reaction pathways that reduce the activation energy. (A) Four different reaction mechanisms of a keto-enol tautomerization. From up to down: Direct transfer of a ...

ABSTRACT: An efficient and facile method for the synthesis of 3-indolyl-substituted phthalides by Friedel-Crafts alkylation of indoles with 3-hydroxyisobenzofuran-1(3H)-one has been developed. Using ...