SUN domain proteins, SUN1 and SUN2, located at the inner nuclear membrane (INM) interact with the nuclear lamins ... be recruited from the nucleoplasm to the NE by overexpressing Myc-tagged pre-Lamin ...

Skeletal Muscle, Piceatannol, Energy Metabolism, SIRT1, Mitochondria Share and Cite: Tsuda, H. , Uchida, T. , Okuno, S. , ...

Peptides are among the most intriguing biomolecules investigated in scientific research. Despite their relatively simple ...

Electrospinning technology can perfectly combine biological signals and topographical cues to synergistically induce directed cell migration and growth. Methods: In this study, poly (caprolactone) ...

the level at which we can deliberately engineer the assembly of microstructures within intracellular environments remains primitive. To overcome this obstacle, we present a platform to reversibly ...

However, the instability of the inserted cells limits the practicality of this technology. Here, the impact of nanoelectrode insertion on intracellular extraction of PEs is characterized with the goal ...

The extracellular ... set of ECM proteins. However, these proteins vary up to 4000-fold between tissues, resulting in highly unique matrix profiles even with the same primary set of proteins. A data ...

Membrane trafficking is the process by which proteins and other macromolecules are distributed throughout the cell, and released to or internalised from the extracellular space. Membrane ...

The two main categories are membrane-associated (31.8%) and transporter (30.2%) proteins, which play direct roles in facilitating interactions between bacterial cells and the extracellular milieu ...

Aside from GE8820, GlycoEra will also use the raise to bring a second program to the clinic and further develop its pipeline of extracellular protein degraders, with a particular focus on immunology ...

The datasets, totaling over 200 GB of mass spectrometry data, include lipid profiles—key components of cell membranes—from 930 samples collected across the Atlantic, Pacific, and Arctic oceans ...