† Department of Chemistry, Infection Innovative Medicines Unit, AstraZeneca-US, 53 Gatehouse Drive, Waltham, Massachusetts 02451, United States ‡ Department of Biosciences, Infection Innovative ...

This Review examines the current evidence supporting a role for intracellular amyloid-β (Aβ) in the pathogenesis of Alzheimer's disease. Intracellular Aβ accumulation appears to be an early ...

While hypolipidemia characterizes VL, LD, a cholesterol auxotroph, relies on host lipid scavenging for its intracellular survival. The aggressive pathology, in terms of increased organ parasite load, ...

Values of p < 0.05 were considered significant. For the hemolytic assay, voluntary donations of human blood were obtained according to the Declaration of Helsinki (Ethical principles for medical ...

Department of Chemistry and Biochemistry, Hampton University, Hampton, Virginia 23668, United States ...

Intracellular signalling peptides and proteins are peptides and proteins involved in transmission of signals (signal transduction) across the membrane of cells. Signals in the form of second ...

A 14-gene molecular assay effectively selects high-risk patients, marking a significant advancement in precision medicine. Future strategies may include AI and personalized vaccines to improve ...

A 14-gene molecular assay may help predict adjuvant chemotherapy benefit in early NSCLC. Patients assigned adjuvant chemotherapy based on molecular risk exhibited a 78% reduction in risk for ...

"These early, interim results from a promising prospective, randomized study evaluating the role of adjuvant chemotherapy in patients with stage IA-IIA non-small cell lung cancer identified as ...

Follow-on interferon-gamma release assay (IGRA) was added for those with tuberculin reaction of 5–14 mm in a pilot programme. Methods This was a prospective cohort study. All household contacts of ...