Immune cells unexpectedly regulate blood sugar levels, offering new insights for managing diabetes, obesity, and cancer.

The gut microbiome, or the community of microorganisms residing in the gastrointestinal tract, has emerged as an important ...

This risk has been attributed to visceral adipose tissue (vAT) expansion associated with increased proinflammatory mediators. Accumulation of CD11c + proinflammatory adipose tissue macrophages (ATM) ...

WGCNA and machine learning models identified 145 markers and five key genes associated with periodontitis. GSVA and CSEA analyses highlighted the JAK- STAT pathway and macrophage involvement in ...

tu-dresden.de Objective The intestinal epithelium is a rapidly renewing tissue which plays central roles in nutrient uptake, barrier function and the prevention of intestinal inflammation. Control of ...

Run a brief analysis at the single-cell level, let’s use the common Seurat pipeline. set.seed(12345) sc <- CreateSeuratObject(counts = sc.counts, project = proj.name, meta.data = sc.meta) sc ## An ...

This indicates a shift in macrophage phenotype from M2 to M1, which is accompanied by downregulation of aberrant sphingosine kinase 1 (SPHK1), phosphorylated YAP, and the YAP target gene CTGF in ...

Pandanus amaryllifolius, a tropical fragrant screw pine, is commonly used in cooking and traditional medicine. Although studies have analysed its metabolite, transcriptome, and proteome profiles, ...

Your intestines spasm and contract ... The key, they show in this new research, is a type of immune cell called a macrophage. Normally, macrophages tamp down the activity of neurons in the ...

The effectiveness of cancer immunotherapy is hindered by mechanisms enabling tumor immune escape and subsequent tumor progression. T cells are essential to the tumor microenvironment, but a deeper ...