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Background Fibrolamellar carcinoma (FLC), a rare and fatal liver cancer lacking effective drug therapy, is driven by the DNAJ-PKAc fusion oncoprotein. However, the underlying mechanism of DNAJ-PKAc’s ...

To address these challenges, we present an optimized workflow that integrates high-purity label-free CTC capture with in-droplet barcoding-based scRNA-seq to achieve higher cell utilization and lower ...

This is because of cells that detach from the original tumor and hide in a dormant state in the breast or other organs. From the earliest stage of embryonic development, through sexual maturation ...