Shandong Laboratory of Yantai Drug Discovery, Bohai Rim Advanced Research Institute for Drug Discovery, Yantai, Shandong 264117, China ...

However, the evidence supporting some of the conclusions remains incomplete, and further mechanistic studies are needed to clarify how miR-283 affects normal aging and influences exercise adaptations.

iPS cardiomyocytes are designed for transplants for patients with severe heart failure who have no effective alternatives other than heart transplant or venticular assist devices. The team hopes ...

Metabolic alterations in cardiomyocytes, along with structural and functional abnormalities, are important pathological features of diabetic cardiomyopathy. The sarcomere, which is the contractile ...

The "iPS heart" displayed on April 2 with a diameter of approximately 3.5 centimeters was built from iPS cells differentiated into cardiomyocytes -- the cells that generate a heartbeat -- and ...

Cardiac-specific Pcsk9 deficiency impairs mitochondrial bioenergetics and heart function and increases mitochondrial cholesterol accumulation in cardiomyocytes. Levels of TSPO (translocator protein) ...