T-cell-based immunotherapies have transformed the treatment, offering cures to subsets of cancer patients. The rate-limiting step in developing safe and effective new immunotherapies is the ...

Sun Yat-sen University, Guangzhou, China.

Cancer vaccines have been a tantalizing idea for decades, but the vast complexity of the human immune system has posed significant challenges. Now, technological advances like rapid DNA sequencing ...

APC, Antigen Presenting Cells, which could be Neutrophils, Dendritic cells, or monocytes/macrophages. Figure prepared using BioRender. Increased tumor infiltration of neutrophils, often accompanied by ...

Chemotherapy regimens chosen by the ChemoID assay dramatically increased ORR in patients with platinum-resistant ovarian cancer. A chemotherapeutic assay (ChemoID) designed to to select targeted ...

It is well known that men are reluctant to see a doctor, especially a urologist. As a result, there is a risk that prostate ...

The incidence of prostate cancer is increasing. Screening with an assay of prostate-specific antigen (PSA) has a high rate for false positive results. Genomewide association studies have ...

uGDB, utilizing next-generation sequencing to detect bladder cancer-associated mutations and DNA alterations, has previously shown associations with recurrence and therapy response.

genome.med.kyoto-u.ac.jp Background Prostate-specific antigen (PSA) is a useful marker for prostate cancer (PCa) and is widely used for screening of PCa ... PSA levels were quantified by ...

Whole-cell tumor vaccines are advantageous because of their ability to induce a broad and multifaceted immune response through the presentation of a wide range of tumor antigens, thereby enhancing the ...