Merck is planning layoffs in Pennsylvania as part of a multi-year plan to wind down operations at a manufacturing plant in ...

Objective: To compare the safety and efficacy of clarithromycin and amoxicillin/clavulanic acid in patients with community-acquired pneumonia due to penicillin ...

in 0.45% sodium chloride injection SP 0.4 mL/min Imipenem Merck 3726J 500 mg (5 mg/mL) in 0.9% sodium chloride injection IV 100 mL/hr Ketorolac Abbott 47359DK 30 mg (15 mg/mL) IVP over 20 sec ...

Antimicrobial resistance (AMR) is a critical global issue, contributing to increased morbidity and mortality, prolonged hospital ...

MSD took a similar approach with its Recarbrio (imipenem/cilastatin-relebactam) product, which was approved by the FDA for cUTIs and complicated intra-abdominal infections (cIAI) in 2019.

We also suggest that the category of ESBLs should be expanded. However, we recently found that the CMY-10 ESBL had higher imipenem-hydrolysing activity than OXA-23, a class D carbapenemase 7,10.

The antibiotics kasugamycin, edeine and GE81112, inhibit translation initiation. Here, the authors present cryo-electron microscopy structures of 30S initiation intermediate complexes with these ...

碳青霉烯类药物在中国上市以来即被广泛应用于各种感染性疾病，同时不可避免的存在不合理和过度使用的情况，导致细菌耐药率的增加，CHINET2024 ...

In the United States, these drugs are not available in oral formulas and are only given through an IV. Carbapenums used in the United States include Primaxin (imipenem), Merrem (meropenem), Invanz ...