2024.07.017]. The scientists determined that Mrc1 and Mcm2 form a co-chaperone complex, ensuring distribution of histones to the lagging strand during DNA replication. In mutants of Mrc1 ...

The fork protection complex (FPC) is a group of proteins, including Mrc1 (Claspin in humans), that play a crucial role in replication of DNA. The new discovery reveals that FPC also recycles parental ...

Chromatin replication is intricately intertwined with the recycling of parental histones to the newly duplicated DNA strands for faithful genetic and epigenetic inheritance ... concentration of the ...

Here, such a chemical proteomics experiment is presented to explore the range of proteins that interact with the N-terminal tail of core histones. Therefore, a core histone consensus ... in regulatory ...

Histones play a crucial role in packaging DNA within the nucleus of eukaryotic cells. The primary function of histones is to help organize and compact the long strands of DNA into a more condensed and ...

At infection sites, neutrophils can release DNA and histones, as parts of neutrophil extracellular traps (NETs), which in ... Bálint for analyzing the scanning electron microscopy images and to Gy.

In archaea, histones play a role in genome compaction and are involved in transcription regulation. Whereas archaeal histones bind DNA without sequence specificity, they bind preferentially to DNA ...

Royalty-free licenses let you pay once to use copyrighted images and video clips in personal and commercial projects on an ongoing basis without requiring additional payments each time you use that ...

Chromatin is made up of monomeric structural units called nucleosomes, which are comprised of DNA wrapped around an octameric core of histone proteins (two copies each of histones H2A, H2B, H3, and H4 ...

The cell has ways to ensure that you can put those modified histones right back, to ensure that information is retained. It's a memory of the state of the gene before DNA replication." Daniel ...