But after a seemingly random finger fracture, his doctor tested him for elevated protein levels in his blood and told him he had a form of cancer called multiple myeloma. It was sort of an out-of ...

Myeloma, or multiple myeloma, is a cancer affecting a particular type of blood cells, called plasma cells. Myeloma is most common in people over 60 and is characterized by the accumulation of ...

Serum levels of polyclonal IgG, IgA and IgM are usually decreased in patients with multiple myeloma (MM); however, little is known about the prognostic significance of polyclonal levels of IgE in ...

Forty-eight patients with multiple myeloma, most of them ambulatory outpatients, at 5 co-operating hospitals,‡ were treated. Patients were entered in the double-blind study by randomized card ...

are bispecific antibodies that activate T cells by targeting CD3 and that have been approved for the treatment of triple-class–exposed relapsed or refractory multiple myeloma. A total of 94 ...

Multiple myeloma is part of the spectrum of diseases ranging from MGUS to plasma cell leukemia, and similar to MGUS, is characterized by proliferation of a plasma cell clone and subsequent ...

multiple sclerosis, and lupus. Immunoglobulin M (IgM) is also one of the first antibodies recruited by the immune system to fight infection. IgM populations rise very quickly when the body is first ...

Individual paraproteinemic disorders exhibit distinct neuropathic phenotypes, often with characteristic, identifiable clinical features. Frequently, prognoses are not well-defined, and in many ...

Patient-derived ACPA clones have been characterised by unique cellular effects and multiple ways to act on the target cells ... RA and is characterised by the presence of antibodies reactive with the ...