Objective To compare the efficacy and safety of oral versus intravenous ibuprofen for the pharmacological closure of patent ductus arteriosus (PDA) in less mature preterm infants. Design Prospective, ...

Am J Health Syst Pharm. 2008;65(24):2347-2357. Administer medications via the oral route when possible. Determine the enteral feeding tube size (e.g., small bore or large bore), insertion site (e ...