Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

Using computational tools and virtual screening, researchers at the Center for Redox Processes in Biomedicine (Redoxoma) have ...

The lab of Dan Xu, PhD, assistant professor at The Hormel Institute, has published a groundbreaking study in Cell Metabolism, ...

The findings could pave the way for new therapies targeting metabolic diseases like obesity and type 2 diabetes.

Four isoforms of JAKs have been described: JAK1, JAK2, JAK3 and TYK2. Oral JAK inhibitors (JAKi) have been developed as synergic anti-cytokine therapy in IBD, showing different selectivity towards JAK ...

This isoform-centric microglia genomic atlas includes 35,879 novel human microglia isoforms identified by long-read RNA sequencing. A multi-ancestry quantitative trait locus meta-analysis of known ...

A former Dunfermline High School pupil has been celebrated for her outstanding research in the field of cancer studies.

Cannabidiol (CBD) is increasingly recognized for its role as an antiseizure medication, especially for the management of Drug-Resistant Epilepsy (DRE). This ...

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