Exploration of the effects of this pathway is underway. An effort to clarify the role of IL-33/ST2 in the crosstalk between end-organ effector cells and their environment, specifically the ...

Interleukin (IL)-23 is a validated therapeutic target in inflammatory bowel disease ... Oral administration of this VHH achieves deep pathway inhibition in a murine colitis model. Furthermore, a ...

This month's cover highlights the article EGFR controls transcriptional and metabolic rewiring in KRASG12D colorectal cancer by Dana Krauß, Maria Sibilia and colleagues. The tumor-intrinsic role of ...

Zai Lab Limited (NASDAQ: ZLAB; HKEX: 9688) today announced new data from its preclinical study of ZL-1503, the Company’s ...

Creative Biolabs recently updated its antibody chip platform, expanding product arrays for phosphorylation signaling and cytokine detection. SHIRLEY, NY, UNITED STATES, May 27, 2025 /EINPresswire.com/ ...

The Interleukin-12 (IL-12) family ligand subunits (IL-12s) and receptor subunits (IL-12Rs) constitute pivotal regulators of immune homeostasis, with direct implications in autoimmune pathologies and ...

IL-12 is a powerful cytokine, a type of protein that acts as a chemical messenger, that plays a key role in initiating the body’s natural immune response. Several studies of IL-12 ...

All of us produce a growth factor—called IL-15—which effectively protects us from cancers. Its role is to boost the ...

The well-studied NF-κB signaling system is a key mediator of the inflammatory response. Large-scale sequencing studies in ...

The Wnt/ß-catenin signaling is a highly conserved pathway that orchestrates several biological functions ... Typically, Research Topics are online and open for submissions within a few weeks and ...

Inflammatory mediators like cytokines and chemokines play a key role in driving age-related and postmenopausal breast cancer progression and immune system changes.