Serotonin can promote both pulmonary vasoconstriction and pulmonary vascular remodeling and is thought to be involved in the pathobiology of PAH. A polymorphism in the serotonin transporter (SERT ...

Objective: Previous research has demonstrated that the hypoxic environment at high altitudes significantly alters the pharmacokinetics of many drugs, reducing their efficacy and increasing adverse ...

A recent study found that placenta-derived IL1 under hypoxic conditions, can greatly increase growth of human stem cell-derived liver organoids. By promoting liver progenitor cell expansion ...

1Department of Surgery, University of Michigan Medical School, Ann Arbor, Michigan. 2Research Service, VA Ann Arbor Healthcare System, Ann Arbor, Michigan.

Moreover, Piezo1 knockout reduced hypoxic pulmonary vasoconstriction in isolated, perfused, and ventilated mouse lungs, endothelial-denuded pulmonary arteries, and hemodynamic measurements in vivo.

1 Geomicrobiology, Marine Geosystems, GEOMAR Helmholtz Centre for Ocean Research Kiel, Kiel, Germany 2 Benthic Biogeochemistry, Marine Geosystems, GEOMAR Helmholtz Centre for Ocean Research Kiel, Kiel ...

Getting a headache during or after exercise can be seriously frustrating – especially if you have kept hydrated to try and stop them from happening. Exercise headaches (also known as "exertional ...