That led to more testing. Quest had three biopsies, two radiology tests, multiple sets of labs and one surgery. Finally, a biopsy came back with the answer McClenathan had been seeking: ...

Kidswell Bio Corporation develops pharmaceuticals for the treatment of rare and intractable diseases in Japan. Its pipeline products include GND-004 for the treatment of ophthalmic disease and ...

Rebecca Kenna has hypoganglionosis, a condition for which there is no known cure. There are only five reported cases of hypoganglionosis in adults across the world. The 29-year-old, who lives in ...

Background: Hypoganglionosis resembles Hirschsprung disease (HSCR) which is characterized by severe constipation. Enterocolitis due to hypoganglionosis or Hirschsprung-associated enterocolitis (HAEC) ...

This ACGME-accredited fellowship provides robust training in disorders of the luminal GI tract, pancreas and hepatic pathology (medical liver including liver transplantation), preparing trainees for a ...

Department of Pediatric Surgery, The Second Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China Institute of Neurobiology, Environment and Genes Related to Diseases Key Laboratory of Chinese ...

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The purpose of this case report is to highlight the radiological and clinical similarity of isolated hypoganglionosis to Hirschsprung disease, making the diagnosis difficult in the early period with ...

Hirschsprung Disease (HSCR) and/or hypoganglionosis are common pediatric disorders that arise from developmental deficiencies of enteric neural crest cells (ENCCs). Retinoid acid (RA) signaling has ...

（本文发表于2014年中华小儿外科杂志，作者：熊晓峰，冯杰雄。转载请注明作者及出处） 巨结肠相关性小肠结肠炎(enterocolitis associated with Hirschsprung’s diseas，HAEC)是先天性巨结肠(Hirschsprung’s disease，H D)常见并发症，发病机制尚不明确，可能与近段肠管机械性 ...