When you have high triglycerides, also known as hypertriglyceridemia, it can lead to several health issues. From impacting ...

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Ionis Pharmaceuticals has reported outcomes from the Phase III Essence study of olezarsen in individuals with moderate ...

Topline data were announced from a phase 3 trial evaluating olezarsen in patients with moderate hypertriglyceridemia with or at risk for ASCVD.

Topline results from the Essence study show that olezarsen significantly lowered mean triglyceride levels compared to placebo ...

The clinical scenarios pertain to managing patients with established (or latent) CVD or an estimated moderate-to-high risk of CVD. These scenarios are essentially encompassed by Type 2 diabetes.

The drug is a promising treatment for severe hypertriglyceridemia, familial chylomicronemia syndrome and other dyslipidemia.

Hypertriglyceridemia (triglycerides 200–499 mg/dL) is relatively common in the United States, whereas more severe triglyceride elevations (very high triglycerides, ≥500 mg/dL) are far less frequently ...

Ionis Pharmaceuticals has reported positive topline outcomes from the randomised, global Phase III Essence study of Tryngolza (olezarsen) in individuals with moderate hypertriglyceridemia and ...