Trials evaluating the use of hypertonic saline solutions for resuscitation after traumatic injury have not shown an overall mortality benefit compared with isotonic fluid administration.

Objectives This research aims to explore the association between serum osmolarity and mortality in patients who are critically ill with specific categories of disease. Design A retrospective cohort ...

Diabetes mellitus (DM) affects the metabolism of primary macronutrients such as proteins, fats, and carbohydrates. Due to the high prevalence of DM, emergency admissions for hyperglycemic crisis, ...

Besides, the consensus recommendations favor high-dose corticosteroid administration. 4, 5 Sztark et al. (1995) were the first to use hypertonic saline in the treatment of potential donors in brain ...

Hypertonic saline (HTS) is an osmotic agent that can help patients in the acute phase of severe traumatic brain injury. HTS extracts fluid from swollen cerebral tissue to both control intracranial ...

Correspondence to: Dr A Durward Paediatric Intensive Care Unit, 9th floor, Guy’s Tower Block, Guy’s Hospital, St Thomas Street, London SE1 9RT, UK; adurwarddoctors.org.uk Intravenous fluid and ...