Pluvia AS has synthesized pharmacological chaperones able to stabilize phenylalanine hydroxylase (PAH) reported to be useful for the treatment of hyperphenylalaninemia, particularly phenylketonuria ...

Stress hyperphenylalaninemia predicts elevated mortality rates in patients with acute decompensated heart failure (ADHF). This study investigated the metabolic pathways underlying this association and ...

Sapropterin Dihydrochloride is used for lowering blood phenylalanine (Phe) levels in adult and pediatric patients aged one month and older suffering from hyperphenylalaninemia (HPA) due to ...

Synlogic has been granted a patent for genetically engineered bacteria and pharmaceutical compositions for modulating and treating diseases related to hyperphenylalaninemia. The patent also includes a ...

The latest research report Hyperphenylalaninemia (HPA) Market, covers various aspects of the industry, including market size, status, trends, and future insights for the next 10 years. It provides a ...

In those affected, there is a reduction in the activity of the enzyme phenylalanine hydroxylase (PAH). This defect impairs the degradation of the amino acid phenylalanine (Phe) into tyrosine (Tyr) and ...

Generic Kuvan is indicated to reduce blood phenylalanine levels in adult and pediatric patients one month of age or older with hyperphenylalaninemia due to tetrahydrobiopterin- (BH4-) responsive ...

Hyperphenylalaninemia (HPA) is the most common amino acid metabolism defect in humans. It is an autosomal-recessive disorder of the phenylalanine (Phe) metabolism, in which high Phe concentrations and ...

Taiwan: A new study published in Critical Care Medicine suggests that stress-induced hyperphenylalaninemia (SHP) in patients admitted to the ICU was associated with a poor ...