Sickle cell anaemia is a genetic blood disorder characterised by the production of an abnormal haemoglobin, known as ...

Samir K Ballas; Franca B Barton; Myron A Waclawiw; Paul Swerdlow; James R Eckman; Charles H Pegelow; Mabel Koshy; Duane R Bonds Baseline QOL results were available on all 299 MSH patients ...

SAN DIEGO -- Treatment with hydroxyurea led to more hematologic dose-limiting toxicities (DLTs) compared with placebo in patients with hemoglobin SC, a milder form of sickle cell disease (SCD), a ...

Compared to drugs that simply ease the symptoms of sickle-cell disease, DMTs can slow disease progression by treating the root cause. For example, the chemo drug hydroxyurea, one of the most used ...

People in England to benefit from groundbreaking one-off gene therapy for severe sickle cell disease approved by NICE ...

Hydroxyurea Significantly Reduces Infections in Children With Sickle Cell Anemia Jan. 29, 2024 — Researchers have revealed that hydroxyurea significantly reduces infections in children with ...

Sickle-cell trait haplotype distribution shows the ... as patients may experience symptoms of differing severity and varied responses to hydroxyurea regardless of haplotype. So, although these ...

Hydroxyurea was used in a 25-year-old man with SCD who had AP and recurrent SP. [21] The patient had received hydralazine, piracetam, and pentoxifylline, but the AP and SP episodes continued over ...

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Sickle cell disease is a group of congenital red ... to relieve symptoms as well as antibiotics to treat infections, hydroxyurea—a bone marrow suppressive agent that decreases red blood cell ...