A new method that successfully designs serine hydrolase enzymes capable of ... amino acid identities, and the chemical structures of bound molecules, allowing for a high degree of precision ...

Background: Infant gut-associated bifidobacteria possess lacto-N-biosidase, which releases lacto-N-biose I (LNB) from human milk oligosaccharides. Results: The crystal structures of lacto-N-biosidase ...