Huntington’s disease is a rare genetic disorder affecting movement, memory, and mood. Here’s what we know—and what’s ahead.

and Huntington's disease, represent a significant and growing global health burden. Despite extensive research, the precise mechanisms underlying these complex diseases are still not fully understood, ...

and McLean Hospital have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to ... The Huntingtin gene provides the genetic ...

The Huntington’s disease treatment market is evolving, with novel therapies targeting mHTT and reshaping the future of neurodegeneration. With the era of symptomatic treatment nearing its limits, ...

Broad Institute researchers have developed a way to edit the genetic sequences at the root of Huntington's disease and Friedreich's ataxia. The conditions are two of more than 40 severe ...

The promiscuity and overlap of receptors and ligands of the PAMP and DAMP systems now present a novel molecular mechanism explaining ... as surrogate markers of disease activity.

Proteinaceous aggregation is a well-known observable in Alzheimer’s disease (AD), but failure and storage of lysosomal bodies within ... long for transporter recognition or release from the lysosome ...

Researchers have developed a gene editing strategy that could repair the genetic problems that lead to Huntington's disease and Friedreich's ataxia. These disorders arise because of abnormal repeats ...

A research team at the University of Barcelona's Institute of Neurosciences (UBneuro) has discovered new molecular mechanisms related to the cognitive decline associated with Alzheimer's disease ...

Chinese researchers recently uncovered molecular evidence supporting Lamarckism—a long-debated theory from the early 19th century that acquired characteristics can be inherited. The evidence was ...