A University of California, Irvine-led research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington's disease and link HD with other ...

More information: Thai B. Nguyen et al, Aberrant splicing in Huntington's disease accompanies disrupted TDP-43 activity and altered m6A RNA modification, Nature Neuroscience (2025). DOI: 10.1038 ...

One of the areas of the brain where these cells congregate is the ventricular zone, which is adjacent to the striatum, a region of the brain devastated by Huntington's disease. The idea that the ...

Scientists from The Hospital for Sick Children (SickKids) and the University of Las Vegas, Nevada (UNLV) have uncovered a ...

The defects in molecular and cellular processes that constitute the triggers of specific pathologies are referred to as mechanisms of disease. Research in this area is vital for designing ...

Research in a mouse model of Huntington’s disease has shown that the adult brain can generate new neurons that integrate into key motor circuits. Building on previous work, the new findings ...

1 First School of Clinical Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China 2 Department of Rehabilitation Medicine, Linyi People’s Hospital, Linyi, China Alzheimer’s ...

The normal functions of peptides that aggregate in Alzheimer’s, Parkinson’s, and Huntington’s have been largely overlooked by scientists, but some argue that they are critical for understanding the ...

One of the areas of the brain where these cells congregate is the ventricular zone, which is adjacent to the striatum, a region of the brain devastated by Huntington's disease. The idea that the ...