Many neurodegenerative diseases are characterized by impairment of protein quality control mechanisms in neuronal ... including Huntington's disease (HD). Playing an integral role in proteostasis ...

The identification of this molecular mechanism sheds light on the ... "The benefits of this study in a disease such as Huntington's, associated with a genetic mutation, is that we can analyze ...

Huntington's disease is a genetic ... the researchers blocked this mechanism pharmacologically and observed improved motor function in mice, and that different molecular values were recovered ...

A University of California, Irvine-led research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington's disease and link HD with other ...

Using an in vitro cell model of Huntington’s disease (HD), researchers ... and the underlying molecular mechanism of this disease still remains elusive," said Wei. "We are continuing our ...

and August Pi i Sunyer Biomedical Research Institute (IDIBAPS), has brought to light new information on the molecular mechanisms that cause Huntington's disease, and defines new pathways to ...

Researchers have identified a key biochemical mechanism relevant to the development of Huntington's Disease ... Professor of Cellular and Molecular Neuroscience at Oxford's Department of ...

Huntington's disease is a genetic ... researchers blocked this mechanism pharmacologically and observed the motor function improved in mice and that different molecular values were recovered ...

We hope this will contribute to improving the strategies in place to find a cure," states the researcher. Related: Study identifies new biomarkers for Huntington's disease Going deeper in molecular ...