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In the mouse model and human tumor samples, MAGE-A4 drives the accumulation of plasma immune cells that suppress antitumor immunity. The study points at novel potential therapeutic avenues that ...
A phase I/II first-in-human study of a novel anti-MAGE-A4 TCR/anti-CD3 bispecific (IMC-C103C) as monotherapy and in combination with atezolizumab in HLA-A*02:01-positive patients with MAGE-A4-positive ...
Researchers at Baylor College of Medicine and collaborating institutions discovered in a mouse model of non-small cell lung cancer that tumors that express protein MAGE-4 and have lost the Pten ...
4月
News Medical on MSNStudy uncovers how MAGE-4 and Pten loss promote aggressive tumor growth - MSNIn the mouse model and human tumor samples, MAGE-4 drives the ... faculty at the Center for Translational Research on Inflammatory Diseases in the Michael E. DeBakey Veterans Affair Medical ...
Now, a team of scientists from Harvard Medical School and MIT have found a way to do similar trick ... In every human, ... That includes the one that introduced MAGE to the world in 2009, ...
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