Exposure to alcohol during the first weeks of embryonic development changes gene activity and cellular metabolism. In ...

Exposure to alcohol during the first weeks of embryonic development changes gene activity and cellular metabolism. In ...

Embryonic stem cells (ESCs) maintain a low translation rate; therefore control of mRNA translation is critical for preserving their stemness. We identified a hitherto unstudied transcription factor, ...

Human development is a beautiful, complex process. Beginning from just two germ cells, the cells divide and double until an entire organism is developed in just under a year.

During embryonic development, thousands of cells divide and move collectively to sculpt the main body axes. Understanding the mechanisms that coordinate this collective behavior remains a ...

During embryonic development, thousands of cells divide and move as one. Understanding the mechanisms that coordinate this collective behavior remains a significant challenge in biology and the ...

Summary: Researchers have created a 3D mouse organoid model to study how neurons in the nose regenerate, revealing that a type of stem cell once considered dormant may be crucial for repairing ...

CRISPR-Cas9 gene editing in blood stem cells, especially with AAV6 vectors, induces DNA damage responses and inflammatory pathways, leading to senescence-like states that impair long-term ...

The human brain is home to around 86 billion neurons, the cells that fire electrical signals to store memories and send information throughout the body. These neurons are well-known for driving how we ...

This first-in-human trial aimed to determine the safety, recommended phase II dose, and antitumor activity of pasritamig, a first-in-class, T-cell–engaging bispecific antibody targeting human ...