Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a ...

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such ...

Cold sore-causing HSV-1 doesn't just hijack cells it reconfigures the entire architecture of our DNA to aid its invasion.

Replicative DNA polymerases (Pol) function with a sliding clamp and their proofreading exonuclease provides high fidelity. Thus, the study of the proofreading mechanism must both contain the Pol–clamp ...

Researchers have discovered that the herpes virus reshapes the human genome’s architecture, rearranging its shape in ...

Researchers have revealed the structural mechanisms of a major DNA repair pathway in human cells ... and the process of 'strand exchange' occurs, but the mechanistic understanding of this last ...

Macquarie University researchers have discovered a naturally occurring protein found in human cells plays a powerful role in ...

“PDI is like a double agent,” Dr Shadfar explains. “In healthy cells, it repairs DNA and helps prevent disease. But in cancer ...

A double-strand DNA break (DSB) occurs or arises when both ... Here, the authors show that transcript RNA serves as a repair template in human cells and identify Polζ as a key factor in RNA ...

Researchers at Northwestern University found that DNA strand separation may require more force than previously thought when modeled in a more true-to-life environment. In most labs, scientists ...

The promise of genome editing to help understand human diseases and create new therapies is vast, but technological ...