The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the ...

Scientists at The Hormel Institute, University of Minnesota, have made a groundbreaking discovery that could lead to new ...

But some plants have taken a different approach. They have evolved sex chromosomes, the bits of DNA that make individual plants either male or female. In that club are organisms like the ginkgo ...

We have studied the role of individual histone N‐termini and the phosphorylation of histone H3 in chromosome condensation. Nucleosomes, reconstituted with histone octamers containing different ...

Researchers from Johns Hopkins University have discovered how histone H3, a protein in roundworm chromosomes, enables offspring to produce specialized cells generations later, challenging the idea ...

Here, by using multiple reaction monitoring (MRM) based LC-MS/MS, we detected dynamic changes of histone H3 lysine post-translational modifications (PTMs). We firstly quantified the precise percentage ...

Unlike the maternal chromatin, which maintains all types of histone H3 methylations throughout embryonic development, paternal chromosomes acquire new and unmodified histones during or after the ...

Here, we analyze the purified LHC with modified peptide and reconstituted semisynthetic mononucleosome substrates. LHC demethylase activity toward methyl-Lys4 in histone H3 is strongly inhibited by H3 ...

Figure 1: Histone H3.3 Ser31 becomes phosphorylated along arms of misaligned chromosomes. To accentuate this difference, we used nocodazole treatment to depolymerize microtubules, allowing the ...

Phosphorylation of histone H3 threonine 118 (H3 T118ph) weakens histone DNA-contacts, disrupting the nucleosome structure. We show that Aurora-A mediated H3 T118ph occurs at pericentromeres and ...