The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the ...

Find more information on the Altmetric Attention Score and how the score is calculated. The coexisting post-translational modifications (PTMs) on histone H3 N-terminal tails were known to crosstalk ...

Scientists at The Hormel Institute, University of Minnesota, have made a groundbreaking discovery that could lead to new ...

Previously, we demonstrated that histone H1 greatly stimulates naked DNA cleavage by this nuclease. Here, we investigate the mechanism of this stimulation with native and recombinant mouse and human ...

Contributed by Steven A. Kliewer; received March 7, 2025; accepted April 29, 2025; reviewed by Bruce M. Spiegelman and Thomas Q. Vallim In this report, we examine how ethanol induces FGF21 expression ...

Researchers identify a novel centromere-specific histone H3 variant called the “CENP ... Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper ...

Centromeres, specialized regions located at the center of chromosomes ... which contain eight histone proteins—two each of H2A, H2B, H3, and H4. However, centromeres feature a specialized ...

The nucleosome is the fundamental repeating unit of chromatin in eukaryotes. In the nucleosome, two histone H2A-H2B dimers and a histone H3-H4 tetramer form the histone octamer, in which 145–147 base ...

Histone H3 Lysine 36 Trimethylation Modification. The histone octamer bearing K36C and C110A mutations on H3 was purified as previously described (35). Trimethylation of the H3K36 was performed using ...