In the present review, we discussed the importance of DNA methylation and histone acetylation on chromatin modifications, regulation of synaptic plasticity gene expression and memory consolidation, ...

histone H3 lysine 4 trimethylation (H3K4me3), histone H3 lysine 27 acetylation (H3K27ac), histone H3 lysine 27 trimethylation (H3K27me3), histone H3 lysine 4 monomethylation (H3K4me1), histone H3 ...

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

Histone post-translational modifications are covalent modifications of histones by phosphorylation on serine or threonine residues, methylation on lysine or arginine, acetylation and deacetylation ...

Researchers uncover a link between genetic mutations and epigenetic changes, two major contributors to aging. Their findings ...

This review focuses on intergenerational and transgenerational epigenetic inheritance in different plants, animal species and ...

Drugs targeting amyloid plaques have failed to show efficacy in clinical trials. A new approach is needed to tackle AD ...

Deregulation of key epigenetic factors and chromatin-modifying proteins, particularly those responsible for the addition, removal or recognition of post-translational histone modifications, are ...

In a groundbreaking study led by Dr. Ying Chen and her team from Ruijin Hospital, Shanghai Jiao Tong University School of ...

A study published in the Journal of Neuroscience sheds new light on how brain cells relay critical information from their ...