The Hippo pathway was discovered as a conserved tumour ... For human cell lines: CTGF-Forward: 5′-CCAATGACAACGCCTCCTG-3′, CTGF-Reverse: 5′-GAGCTTTCTGGCTGCACCA-3′, CYR61-Forward: 5 ...

Now, researchers at Osaka University have identified the disturbed molecular pathways and revealed the underlying mechanisms that may inform an effective and much-needed therapeutic strategy.

Among these signals, the TGF-β and HIPPO pathways are critical, functioning as tumor suppressors and regulating liver development and regeneration. The review focuses on these pathways' interplay ...

Researchers report that the Hippo pathway is important for maintaining adult murine cardiac fibroblasts in their resting state. A group of researchers at Baylor College of Medicine, the Texas ...

The Hippo signaling pathway, a genetic program thought to play a central role in organ development, does not lead to normal organ growth in flies and mice, according to a new study “Hippo ...

Among these signals, the TGF-β and HIPPO pathways are critical, functioning as tumor suppressors and regulating liver development and regeneration. The review focuses on these pathways' interplay ...

The research examined the Hippo signaling pathway, an evolutionarily conserved signaling pathway that plays a complex role in cellular function as a major pathway promoting fibrosis in systemic ...

The article, "Dysregulation of PI3K and hippo signaling pathways synergistically induces chronic pancreatitis via Ctgf upregulation" was published in the Journal of Clinical Investigation at DOI ...