Background and aims: The iron regulatory hormone hepcidin has not been studied in infants, who experience large physiological changes in iron status. The objective was to study hepcidin and its ...

New research highlights how elevated levels of the iron-regulating hormone hepcidin contribute to psoriasis by driving skin ...

Hepcidin, a liver-derived hormone, regulates iron homeostasis by inhibiting intestinal iron absorption and iron release from macrophages. In β-thalassemia, hepcidin levels are inappropriately low ...

Hereditary hemochromatosis is an inherited iron overload disorder caused by inappropriately low hepcidin secretion leading to increased duodenal absorption of dietary iron, most commonly in C282Y ...

Weinstock and colleagues hypothesize that inflammation associated with Crohn's disease could increase levels of hepcidin, which affects iron transport. Increased levels of hepcidin could ...

Ionis’ drug, called sapablursen, is currently being tested in a Phase 2 trial in people with polycythemia vera.

A Prospective, Randomized, Interventional Study of Oral Iron Supplementation Comparing Daily Dose with Alternate Day Regimen Using Hepcidin as a Biomarker in Iron Deficiency Anemia. Lactate-free ...

The idea is that this increases the expression of hepcidin, which is the key regulator of iron homeostasis, thereby helping treat various blood diseases. Sapablursen is currently in a phase 2 ...