Inspired by hepatic lobules, a novel artificial liver was developed by assembling morphological cell sheets with high accuracy in terms of cell type, density, and distribution. By simulating the ...

Seeking to find an answer to this significant medical question, scientists in Germany have gained new insights into the underlying processes involved in the regeneration of liver lobules using ...

The liver exhibits metabolic zonation, with gene expression and metabolic functions distributed across specific zones along ...

Scientists from TU Wien and Keio University have developed a scalable method to create artificial blood vessels in ...

In biomedical research, so-called organs-on-a-chip, also referred to as microphysiological systems, are becoming increasingly important: by cultivating tissue structures in precisely controlled ...

Its fundamental functional unit, the hepatic lobule, features a hexagonal design with a central vein at its core, while the hepatic artery and portal vein provide oxygen and nutrients from the ...

A new study titled "Biomimetic hepatic lobules from three-dimensional imprinted cell sheets" has been led by Prof. Yuanjin Zhao of the Department of Hepatobiliary Surgery, Hepatobiliary Institute ...

The necrosis is invariably central and involves the parenchyma completely and uniformly so that in most cases only a rim of liver cells is seen at the periphery of the lobule. Reticulum staining ...

Inspired by hepatic lobules, a novel artificial liver was developed by assembling morphological cell sheets with high accuracy in terms of cell type, density, and distribution. By simulating the ...