† † Vanderbilt Institute of Chemical Biology and ‡ Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States § Department of ...

Award-winning research presented by Hangjie Fu at EHA shows that ellagic acid can protect against iron overload-induced liver ...

A blood test based on whole-genome sequencing achieved 99% sensitivity and specificity for detecting HPV-positive head and neck cancer. Early postoperative detection of circulating tumor DNA ...

Positive updates across all programs, including longer term efficacy and safety data from the HELIOS open-label extension trial of bitopertin in erythropoietic protoporphyria (EPP), additional ...

Heme oxygenase catalyzes the first step in the oxidative degradation of heme. The crystal structure of heme oxygenase-1 (HO-1) reported here reveals a novel helical fold with the heme sandwiched ...

(22) Little is known about RufO’s catalysis, including the substrate recognition mechanism, the changes at the catalytic site and overall protein structure in response to peptide binding, the ...

Heme biosynthesis is a very controlled process that occurs on every nucleated cell types, involving both mitochondrial and cytoplasmatic enzymatic pathways (Shemin 1989). The major part of all heme in ...

Disc Medicine, Inc. (NASDAQ:IRON), a clinical-stage biopharmaceutical company focused on the discovery, development, and commercialization of novel treatments for patients suffering from serious ...