Biosynthesis is the generation of natural products through enzymatic reactions, as in cellular metabolism. Successive enzymatic reactions by a number of enzymes are generally required to achieve a ...

Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 7, Groningen 9747 AG, The Netherlands Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, Groningen ...

Mitochondrial iron levels decreased, while cytosolic iron levels significantly increased. The excessive cytosolic iron stimulated the overproduction of heme, a major component of hemoglobin important ...

The excessive cytosolic iron stimulated the overproduction of heme, a major component of hemoglobin important for oxygen transport in red blood cells. Subsequently, the surplus accumulation of ...

Excess cytosolic iron then stimulates heme biosynthesis and the excess heme induces stress in red blood cells, ultimately resulting in anemia. Most of the proteins are synthesized in the cytosol.

Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana─Champaign, Urbana, Illinois 61801, United States Department of Materials Science and Engineering, University of ...

These include the species Ruminococcus callidus from the Firmicutes phylum (OR = 0.937, 95% CI = 0.882–0.996), the ADP-L-glycero-beta-D-manno-heptose biosynthesis pathway (OR = 0.930, 95% CI = 0.875–0 ...

Aldosterone synthase inhibitors inhibit biosynthesis of aldosterone, so you are not making as much aldosterone, and that is the big difference.” Researchers analyzed data from 285 adults with ...