Fuster, JJ, MacLauchlan, S, Zuriaga, MA, et al. Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice. Science 2017;355:842-847 Crossref ...

Early stages in cancer development might be present years before cancers become ... Clonal hematopoiesis with somatic mutations was observed in 10% of persons older than 65 years of age but in ...

Atherosclerosis can speed up the development of clonal hematopoiesis. Download PDF Copy; Reviewed. Reviewed by Emily Henderson, B.Sc. Feb 27 2021.

Atherosclerosis (cardiovascular disease) causes clonal hematopoiesis a common age-related condition in which the descendants of one of these hematopoietic stem cells begin to dominate.

Simply, hematopoiesis is the process through which the body manufactures blood cells.It begins early in the development of an embryo, well before birth, and continues for the life of an individual.

The study showed that smoking accelerates the development of clonal hematopoiesis in a dose-dependent manner and that all the associated nonhematological diseases are likely tied to smoking behavior.

Researchers pinpoint a cellular process called 'clonal hematopoiesis' as a new risk factor for cardiovascular problems. In the future, this may lead to targeted, personalized treatments.

Atherosclerosis can accelerate the development of clonal hematopoiesis, study finds. Your friend's email. Your email. I would like to subscribe to Science X Newsletter. Learn more. Your name.

More information: Tomoaki Ueda et al, Endothelial Cell-Selective Adhesion Molecule Contributes to the Development of Definitive Hematopoiesis in the Fetal Liver, Stem Cell Reports (2019). DOI: 10. ...

"The development of extramedullary hematopoiesis in the spleen is dependent on the capacity of NK cells to prevent virus spread by effectively eliminating infected cells," Jordan explains.