The superfamily 1 (SF1) and SF2 enzymes are non-hexameric enzymes possessing both helicase and single-stranded DNA (ssDNA) translocase activities, as well as the ability to displace proteins from DNA.

How does the cell protect these strands from damage? How would you identify the protein that serves as a connector between DNA helicase and pol-a/primase? A simple yet often effective approach is ...

The company announced the completion of an investigational new drug (IND) application submission for NDI-219216, a novel Werner syndrome helicase (WRN) inhibitor in development for the treatment ...

A search for Npw38-interacting molecules revealed that Npw38 can interact with NpwBP, DNA helicase, RNA helicase, RNA, and single-stranded DNA to form a nuclear protein complex which may be involved ...