Metal-dependent DNA and RNA nucleases are enzymes that cleave nucleic acids with great efficiency and precision. These enzyme-mediated hydrolytic reactions are fundamental for the replication, repair, ...

Pseudoisocytosine (J), a neutral analogue of protonated cytosine, is currently the gold standard modified nucleobase in peptide nucleic acids (PNAs) for the formation of J·G-C triplets that are stable ...

Liam Longo, a protein historian at the Tokyo Earth-Life Science Institute, was examining a protein fragment, or peptide, that recognizes nucleic acids and is commonly found in DNA-repair enzymes.