It also claims that Ultragenyx was aware of the origins of the HeLa cell line, but never sought or received permission from the estate of Henrietta Lacks to use them. The biotech – which has a ...

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Maryland lawmakers introduced a bill Monday to posthumously award Henrietta Lacks a Congressional Gold Medal for her ...

为解决Cas9衍生碱基编辑器 (BE)在多重编辑和旁观突变 (BM)控制上的技术瓶颈，耶鲁大学团队开发了6种Cas12a衍生BE系统，通过优化gRNA阵列架构和引入截短gRNA策略，首次实现单细胞15个基因组位点的同步编辑（效率达71.3%），并将旁观突变降低50%。该研究发表于《Nature Communications》，为多基因疾病建模和合成基因组工程提供了突破性工具。

RNA作为一种重要的生物大分子，具有超过100种化学修饰，也因此孕育了一门新兴学科—表观转录组学。在常规认知中，糖基化发生在蛋白质和脂质表面，介导细胞通讯或分子间的相互作用。截止2021年，还尚未发现RNA和多糖之间存在直接联系。 2019年，斯坦福大学Carolyn R. Bertozzi教授课题组的博士后Ryan A. Flynn首次发现在细胞表面存在被糖基化修饰的RNA——glycoRNA。

This study identifies 53BP1 as an interaction partner of GMCL1 (a likely CUL3 substrate receptor). The study seeks to link this finding to regulation of the mitotic surveillance pathway and paclitaxel ...

Lacks' immortal cells were taken without her consent in 1951 and used for research that changed the course of modern medicine ...

A new green synthesis method uses laser ablation of bay leaves in PBS to create fluorescent carbon dots with stable blue ...