It also claims that Ultragenyx was aware of the origins of the HeLa cell line, but never sought or received permission from the estate of Henrietta Lacks to use them. The biotech – which has a ...

为解决Cas9衍生碱基编辑器 (BE)在多重编辑和旁观突变 (BM)控制上的技术瓶颈，耶鲁大学团队开发了6种Cas12a衍生BE系统，通过优化gRNA阵列架构和引入截短gRNA策略，首次实现单细胞15个基因组位点的同步编辑（效率达71.3%），并将旁观突变降低50%。该研究发表于《Nature Communications》，为多基因疾病建模和合成基因组工程提供了突破性工具。

A new green synthesis method uses laser ablation of bay leaves in PBS to create fluorescent carbon dots with stable blue ...

Cell biology is the discipline of biological sciences that studies the structure, physiology, growth, reproduction and death of cells. Research in cell biology uses microscopic and molecular tools ...

In a comprehensive Genomic Press interview published today, Professor Barbara Franke unveils her remarkable scientific ...

真核生物细胞核是细胞遗传与代谢的控制中心，内部高度组织化，形成诸多无膜区室，称为细胞核亚结构。这些由DNA、RNA和蛋白质组成的细胞核亚结构组成和形态各异，参与基因表达调控，具有重要的生理意义。核应激小体是灵长类动物细胞在应对如亚砷酸钠、热休克等不同理化刺激时形成的特有的细胞核亚结构，由微卫星重复序列 Satellite III ( SatIII) DNA、 SatIII ...