Nat Clin Pract Cardiovasc Med. 2007;4(3):136-142. In addition, identification of tag SNPs associated with a given disease allows the HapMap to be used to quickly find candidate genes that can ...
University of Tokyo researchers have investigated the origin and dispersal scenarios of Homo sapiens into East Eurasia. The team examined how migration routes, genetic contributions from archaic ...
Genomic evidence from large-scale projects, including the HapMap Project and 1000 Genomes Project, confirmed that modern non-African populations share a common ancestor who left Africa ...
Most common diseases and most quantitative traits that can be measured in human populations are complex genetic traits. That is, many genetic and nongenetic factors interact to determine the final ...
Most psychiatric disorders are highly heritable, yet few reproducible genetic risk factors have been identified by linkage analysis and candidate gene or genome-wide association studies.
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Purpose: The basic concepts of pharmacogenetics, pharmacogenetic study approaches, factors to consider when applying pharmacogenetic discoveries to patient care, and potential roles for ...
After an illustrious career, including 12 years as director of the NIH and leading the HGP consortium, Francis Collins announces his sudden resignation.
This valuable study confirms the association between the human leukocyte antigen (HLA)-II region and tuberculosis (TB) susceptibility in genetically admixed South African populations, specifically ...