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国药I3C多肽链复合素促进HPV清除及宫颈上皮内瘤变逆转的临床与机制 ...
本文通过临床试验与分子实验,首次揭示I3C-PC在HPV相关病变中的多靶点干预机制。 主要终点:3个月HPV转阴率(HPV DNA阴性); 次要终点:9个月CIN逆转率(病理降级或消退); 探索性终点:E6/E7 mRNA表达水平、宫颈局部免疫细胞密度。 液相色谱-质谱(LC-MS ...
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