Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

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Following this transient activation, the HPG axis becomes dormant through a combination of gonadal and non-gonadal inhibitory mechanisms (Yao et al., 2021). These physiological changes highlight how ...

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OBJECTIVE Angiotensin II (AII) and aldosterone are not always fully suppressed during chronic angiotensin converting enzyme (ACE) inhibitor treatment. In congestive heart failure (CHF) such failure of ...

The release of aldosterone is typically controlled by the renin-angiotensin aldosterone system, situated in the adrenal glands, kidneys, and lungs. Here, we reveal that the class A scavenger receptor ...