Human immunodeficiency virus type 1 (HIV-1) targets important cells of our immune system, making infected individuals more vulnerable to diseases and infections. Once inside human cells ...

11, 2024 — Investigators who previously found that a daily statin pill helps prevent heart attacks and strokes ... among people living with HIV who didn't respond to prior ...

22, 2025 — Pathogen-fighting immune cells called tissue-resident memory CD8 T cells (TRM cells) go through a surprising transformation -- and relocation -- as they fight infections in the small ...

The findings could lead to more precise engineering of CAR-T cells, allowing them to attack cancer more effectively while potentially alleviating some of the side-effects of the therapy ...

Measuring CD4 T-cells is important in helping healthcare providers determine the stage and likely outcome of HIV infection. While they are no longer used to determine when HIV therapy should be ...

Caregiving can take many forms, often requiring a profound shift in daily life. While navigating a disease is an immense ...

Here, Olari et al show that alpha-synuclein enhances HIV-1 entry and replication in human T cells, macrophages and microglia which may contribute to the development of neurodegenerative disease.

Intense global research is now exploring the clinical potential of CAR T-cell therapies beyond blood cancers, with therapies in development targeting solid tumours, autoimmune diseases, and infectious ...

The scientists used data from the LJI-led Immune Epitope Database (IEDB) to identify exactly how human T cells attack key proteins (epitopes) on seasonal flu viruses. They then developed a ...