Glycine can stimulate or inhibit neurons in the brain, thereby controlling complex functions. Unraveling the three-dimensional structure of the glycine transporter, researchers have now come a big ...

Determination of glycine transporter opens new avenues in development of psychiatric drugs. ScienceDaily . Retrieved April 7, 2025 from www.sciencedaily.com / releases / 2021 / 03 / 210304112506.htm ...

Glycine transporter GlyT1 is the main regulator of neurotransmitter glycine levels in the brain, and also important for e.g. blood cells, where glycine is required for the synthesis of heme.

A novel glycine transporter inhibitor improved cognition after 12 weeks among individuals with schizophrenia, according to results of a double-blind, randomized, placebo-controlled phase 2 study ...

Glyzin und GABA sind die beiden wichtigsten hemmenden Botenstoffe im zentralen Nervensystem. Störungen der hemmenden Erregungsübertragung konnten bereits mit neurologischen Erkrankungen wie Epilepsie ...

The Company will evaluate the efficacy and safety of BI 425809 in the CONNEX trial program, which includes the phase 3 CONNEX-1 (ClinicalTrials.gov: NCT04846868), CONNEX-2 (ClinicalTrials.gov ...

Glycine transporter 1 (GlyT1), a glycine transporter protein, is highly co-localized with the NMDA receptor. Inhibition of GlyT1 can increase the concentration of glycine in the synaptic cleft, ...

Unraveling the three-dimensional structure of the glycine transporter, researchers have now come a big step closer to understanding the regulation of glycine in the brain. These result open up ...

Researchers have uncovered the structure of Glycine Transporter 1, it enables the uptake of glycine into neurons and acts as a neurotransmitter in the brain. This new information could open new ...