Determination of glycine transporter opens new avenues in development of psychiatric drugs. ScienceDaily . Retrieved April 7, 2025 from www.sciencedaily.com / releases / 2021 / 03 / 210304112506.htm ...

Unraveling the three-dimensional structure of the glycine transporter, researchers have now come a big step closer to understanding the regulation of glycine in the brain. These results ...

Glycine transporter GlyT1 is the main regulator of neurotransmitter glycine levels in the brain, and also important for e.g. blood cells, where glycine is required for the synthesis of heme.

Here, the analysis of genetically modified mice revealed two novel disease genes associated with malfunctioning of inhibitory synapses, the collybistin and the glycine transporter 2 genes. Genetic ...

The Company will evaluate the efficacy and safety of BI 425809 in the CONNEX trial program, which includes the phase 3 CONNEX-1 (ClinicalTrials.gov: NCT04846868), CONNEX-2 (ClinicalTrials.gov ...

Please provide your email address to receive an email when new articles are posted on . A novel glycine transporter inhibitor improved cognition after 12 weeks among individuals with schizophrenia ...

Glycine transporter 1 (GlyT1), a glycine transporter protein, is highly co-localized with the NMDA receptor. Inhibition of GlyT1 can increase the concentration of glycine in the synaptic cleft ...

Caption Unraveling the three-dimensional structure of the glycine transporter, researchers have now come a big step closer to understanding the regulation of glycine in the brain. These result ...

Researchers have uncovered the structure of Glycine Transporter 1, it enables the uptake of glycine into neurons and acts as a neurotransmitter in the brain. This new information could open new ...

This could be done using inhibitors targeting Glycine Transporter 1 (GlyT1), a protein that sits in neuronal cell membranes and is responsible for the uptake of glycine into neurons. However, the ...