The reaction is catalyzed by the enzyme bilirubin UDPglucuronyl transferase, with uridine diphosphoglucuronic acid (UDPCA) serving as the glucuronyl donor. Deficiency of the enzyme, which has been ...

Because glucuronyl transferase catalyzes the conjugation of bilirubin, a deficiency of the enzyme in newborn infants can result in jaundice. Another consequence of this deficiency is an increased ...

Extract: The bilirubin-UDP-glucuronyl transferase (BGT) activity in liver of newborn rats was measured to determine if unconjugated bilirubin could be the trigger substance of glucuronyl ...

In the liver, the bilirubin is conjugated with glucuronic acid (catalyzed by UDP-glucuronyl transferase) to give bilirubin diglucuronide or “conjugated” bilirubin, which is the water soluble ...

Administration of phenobarbital has been used to induce glucuronyl transferase in newborn infants and can reduce, rather than exacerbate, neonatal jaundice. Other factors that reduce the amount of ...

The absolute bioavailability of EC mycophenolate sodium is 72%. MPA undergoes hepatic metabolism by glucuronyl transferase to the inactive mycophenolic acid glucuronide (MPAG), the predominant ...

served as glucuronide acceptor hepatic glucuronyl transferase activity declined gradually to 25 % of normal 7 days post-hypophysectomy and 18 days post-thyroidectomy. In hypox rats, the OAP ...