Liquid-liquid phase separation (LLPS) is a pivotal biophysical phenomenon that plays a critical ... weak interactions to form enriched liquid-like microenvironments within cells, resulting in two ...

This important paper describes the regulatory pathway of rRNA synthesis by Meioc-Piwil1 in germ cell differentiation in zebrafish. Using the molecular genetic and cytological approaches, the authors ...

The eukaryotic cell, the most significant increase in complexity in the history of life's evolution on Earth, emerged as a phase transition and unlocked the path toward other major transitions ...

Testicular germ cell tumours (TGCTs) are the most common malignancy in men 15-35 years of age. Management options for men with TGCTs include surgery, radiation and/or chemotherapy. Given TGCTs' ...

The first patient with small cell lung cancer has been dosed in a phase 1/2 trial investigating first-line iadademstat plus immune checkpoint inhibitors. The first patient with small cell lung cancer ...

Analysis of cell movement using label-free phase-contrast microscopy enables differentiation between healthy fibroblasts and cancerous fibrosarcoma cells with up to 94% accuracy.

The Phase 2 trial is a multi-center, single-arm, two-stage, open-label study designed to evaluate the safety and efficacy of MB-105 in patients with relapsed or refractory CD5-positive T-cell lymphoma ...

Researchers from Tokyo Metropolitan University in Japan on Saturday said they have found that the motion of unlabelled cells can be used to tell whether they are cancerous or healthy. They ...

Background Fibrolamellar carcinoma (FLC), a rare and fatal liver cancer lacking effective drug therapy, is driven by the DNAJ-PKAc fusion oncoprotein. However, the underlying mechanism of DNAJ-PKAc’s ...