DeepMind has launched AlphaGenome, a new artificial intelligence (AI) model that can predict how single DNA variants affect gene regulation across the human genome. The model, now available via API ...

Analytic flow combining single-cell transcript data with WGS analysis. A liver disease related to metabolic abnormalities ...

Human Papillomavirus: Gene Expression, Regulation and Prospects for Novel Diagnostic Methods and Antiviral Therapies Sheila V Graham Disclosures Future Microbiol. 2010;5 (10):1493-1506. 0 ...

Cracking the genome's switchboard: How AI helps decode gene regulation by Aliyah Kovner, Lawrence Berkeley National Laboratory edited by Lisa Lock, reviewed by Robert Egan Editors' notes ...

A team of scientists at the MRC Laboratory of Medical Sciences (LMS) has uncovered a previously unknown mechanism that ...

Gene regulation in immune cells refers to the mechanisms used by immune cells to increase or decrease the production of specific gene products. Development of T cells in the thymus results in ...

Here, we develop a method for controlling gene expression based on Cas9, an RNA-guided DNA endonuclease from a type II CRISPR system. The authors show that a catalytically dead Cas9 lacking ...

Review Article Published: April 2009 β-Catenin hits chromatin: regulation of Wnt target gene activation Christian Mosimann, George Hausmann & Konrad Basler Nature Reviews Molecular Cell Biology ...

A team of scientists at the MRC Laboratory of Medical Sciences (LMS) has uncovered a previously unknown mechanism that ...

The duration of expression of the gene Cdx2 is tightly regulated by a newly identified DNA sequence element called an “attenuator.” ...

Alcohol alters gene function in the differentiating cells of the embryo, study finds by University of Eastern Finland edited by Lisa Lock, reviewed by Robert Egan Editors' notes ...

The research was led by Dr Irène Amblard and Dr Vicki Metzis from the Development and Transcriptional Control group, in ...