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10 17 18 Vector expression in transduced cells, particularly when the vector expresses a transgene such as GFP, is technically simple and can estimate functional titer. 16 The limitations of this ...
1B). In all cases, the flap sequence significantly enhanced GFP transduction mediated by the HIV vector. Figure 1: The HIV-1 central DNA flap enhances gene transduction of primary neural cells.
In mouse studies, the JUST-AAV vector achieved 77-fold higher expression of green fluorescent protein (GFP) in the brain compared to AAV9, while reducing the tropism to the liver by 99%.
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