Orange, positive z-score; white, zero z-score. OBs=osteoblasts; OCs=osteoclasts. (F) GATA4 IHC of healthy human cartilage tissue from young and aged donors. Bar=50 µm. (G) Relative protein levels of ...

David Alvarez-Ponce, an associate professor and bioinformatician at the University of Nevada, Reno, along with his coauthor and former graduate student Krishnamurthy Subramanian, currently at the ...

The protein domain that is responsible for the recognition of collagen has previously been mistaken for a subform of another. Dr. Oliver Arnolds and Professor Raphael Stoll from the Faculty of ...

Transcription factor GATA4, which plays an important role in SASP and cell aging regulation, was identified when studying the influencing factors of cell aging. GATA4 protein, but not its mRNA, ...

BRD4 (bromodomain-containing protein 4), a member of the BET (bromo- and extraterminal domain) family of ubiquitously expressed acetyl-lysine reader proteins, plays a pivotal role as a coactivator of ...

BRD4 (bromodomain-containing protein 4), a member of the BET (bromo- and extraterminal domain) family of ubiquitously expressed acetyl-lysine reader ... and preferentially colocalizes with GATA4 (GATA ...

Herein, a program, Protein Surface Printer (PSP), is built that performs multiple functions in quantifying protein surface domains. Two proteins, PETase and cytochrome P450, are used to validate that ...

Genomes appear similar to natural language texts, and protein domains can be treated as analogs of words. To investigate the linguistic properties of genomes further, we calculated the complexity of ...

Silencing of GATA4 in cultured neonatal rat ventricular myocytes significantly diminishes ... 10 Glucose-regulated protein of 78 kDa (GRP78)—the most abundant ER-resident chaperone—interacts with ...