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Figure 1: Functional domains and essential amino acids in mouse GATA-binding protein 3. Figure 2: Transcriptional regulation of positive selection, CD4- or CD8-lineage commitment and post ...
Figure 1: Ribbon diagram, surface and density maps, and amino acid sequence of the protein 4.1R core domain. Figure 2: Space filling representation and stereo view of the protein 4.1R core domain ...
† Department of Pediatrics, University of British Columbia, Vancouver, British Columbia V5Z 4H4, Canada ∥ Michael Cuccione Childhood Cancer Research Program, BC Children’s Hospital Research Institute, ...
Orange, positive z-score; white, zero z-score. OBs=osteoblasts; OCs=osteoclasts. (F) GATA4 IHC of healthy human cartilage tissue from young and aged donors. Bar=50 µm. (G) Relative protein levels of ...
Plasma protein binding is crucial for understanding pharmacokinetics, pharmacodynamics, and safety. However, it is often not considered to be a primary parameter for optimization in drug design. This ...
GlycoEra will funnel part of the money to advance its lead asset, an IgG4-targeted protein degrader dubbed GE8820 that selectively targets and depletes IgG4 autoantibodies. GE8820 works “with a speed, ...